Economic and operational impact of an improved pathway using rapid molecular diagnostic testing for patients with influenza-like illness in a German emergency department.
Identifieur interne : 000020 ( Main/Exploration ); précédent : 000019; suivant : 000021Economic and operational impact of an improved pathway using rapid molecular diagnostic testing for patients with influenza-like illness in a German emergency department.
Auteurs : Matthias Brachmann [Allemagne] ; Katja Kikull [Allemagne] ; Clemens Kill [Allemagne] ; Susanne Betz [Allemagne]Source :
- Journal of clinical monitoring and computing [ 1573-2614 ] ; 2019.
Descripteurs français
- KwdFr :
- Allemagne (MeSH), Coûts des soins de santé (MeSH), Grippe humaine (diagnostic), Grippe humaine (économie), Humains (MeSH), Modèles d'organisation (MeSH), Patients hospitalisés (MeSH), Réaction de polymérisation en chaîne (MeSH), Service hospitalier d'urgences (MeSH), Techniques de diagnostic moléculaire (méthodes), Techniques de diagnostic moléculaire (économie), Études rétrospectives (MeSH).
- MESH :
- diagnostic : Grippe humaine.
- méthodes : Techniques de diagnostic moléculaire.
- économie : Grippe humaine, Techniques de diagnostic moléculaire.
- Allemagne, Coûts des soins de santé, Humains, Modèles d'organisation, Patients hospitalisés, Réaction de polymérisation en chaîne, Service hospitalier d'urgences, Études rétrospectives.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Emergency Service, Hospital (MeSH), Germany (MeSH), Health Care Costs (MeSH), Humans (MeSH), Influenza, Human (diagnosis), Influenza, Human (economics), Inpatients (MeSH), Models, Organizational (MeSH), Molecular Diagnostic Techniques (economics), Molecular Diagnostic Techniques (methods), Polymerase Chain Reaction (MeSH), Retrospective Studies (MeSH).
- MESH :
- geographic : Germany.
- diagnosis : Influenza, Human.
- economics : Influenza, Human, Molecular Diagnostic Techniques.
- methods : Molecular Diagnostic Techniques.
- Emergency Service, Hospital, Health Care Costs, Humans, Inpatients, Models, Organizational, Polymerase Chain Reaction, Retrospective Studies.
Abstract
To evaluate the economic and operational effects of implementing a shorted diagnostic pathway during influenza epidemics. This retrospective study used emergency department (ED) data from the 2014/2015 influenza season. Alere i influenza A & B rapid molecular diagnostic test (RDT) was compared with the polymerase chain reaction (PCR) pathway. Differences in room occupancy time in the ED and inpatient ward and cost differences were calculated for the 14-week influenza season. The process flow was more streamlined with the RDT pathway, and the necessary isolation time in the ED was 9 h lower than for PCR. The difference in the ED examination room occupancy time was 2.9 h per patient on a weekday and 4 h per patient on a weekend day, and the difference in the inpatient room occupancy time was 2 h per patient on a weekday and 3 h per patient on a weekend day. Extrapolated time differences across the influenza season were projected to be 2733 h in the ED examination room occupancy and 1440 h in inpatient room occupancy. In patients with a negative diagnosis, the RDT was also estimated to reduce the total diagnostic costs by 41.52 € per patient compared with PCR. The total cost difference was projected to be 31,892 € across a 14-week influenza season. The improved process and earlier diagnosis with the RDT pathway compared with conventional PCR resulted in considerable savings in ED, inpatient room occupancy time and cost across the influenza season.
DOI: 10.1007/s10877-018-00243-2
PubMed: 30610515
PubMed Central: PMC6823314
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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xml:lang="en"><term>Emergency Service, Hospital (MeSH)</term><term>Germany (MeSH)</term><term>Health Care Costs (MeSH)</term><term>Humans (MeSH)</term><term>Influenza, Human (diagnosis)</term><term>Influenza, Human (economics)</term><term>Inpatients (MeSH)</term><term>Models, Organizational (MeSH)</term><term>Molecular Diagnostic Techniques (economics)</term><term>Molecular Diagnostic Techniques (methods)</term><term>Polymerase Chain Reaction (MeSH)</term><term>Retrospective Studies (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Allemagne (MeSH)</term><term>Coûts des soins de santé (MeSH)</term><term>Grippe humaine (diagnostic)</term><term>Grippe humaine (économie)</term><term>Humains (MeSH)</term><term>Modèles d'organisation (MeSH)</term><term>Patients hospitalisés (MeSH)</term><term>Réaction de polymérisation en chaîne (MeSH)</term><term>Service hospitalier d'urgences (MeSH)</term><term>Techniques de diagnostic moléculaire (méthodes)</term><term>Techniques de diagnostic moléculaire (économie)</term><term>Études rétrospectives (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Germany</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="economics" xml:lang="en"><term>Influenza, Human</term><term>Molecular Diagnostic Techniques</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Molecular Diagnostic Techniques</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Techniques de diagnostic moléculaire</term></keywords><keywords scheme="MESH" qualifier="économie" xml:lang="fr"><term>Grippe humaine</term><term>Techniques de diagnostic moléculaire</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Emergency Service, Hospital</term><term>Health Care Costs</term><term>Humans</term><term>Inpatients</term><term>Models, Organizational</term><term>Polymerase Chain Reaction</term><term>Retrospective Studies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Allemagne</term><term>Coûts des soins de santé</term><term>Humains</term><term>Modèles d'organisation</term><term>Patients hospitalisés</term><term>Réaction de polymérisation en chaîne</term><term>Service hospitalier d'urgences</term><term>Études rétrospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Allemagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To evaluate the economic and operational effects of implementing a shorted diagnostic pathway during influenza epidemics. This retrospective study used emergency department (ED) data from the 2014/2015 influenza season. Alere i influenza A & B rapid molecular diagnostic test (RDT) was compared with the polymerase chain reaction (PCR) pathway. Differences in room occupancy time in the ED and inpatient ward and cost differences were calculated for the 14-week influenza season. The process flow was more streamlined with the RDT pathway, and the necessary isolation time in the ED was 9 h lower than for PCR. The difference in the ED examination room occupancy time was 2.9 h per patient on a weekday and 4 h per patient on a weekend day, and the difference in the inpatient room occupancy time was 2 h per patient on a weekday and 3 h per patient on a weekend day. Extrapolated time differences across the influenza season were projected to be 2733 h in the ED examination room occupancy and 1440 h in inpatient room occupancy. In patients with a negative diagnosis, the RDT was also estimated to reduce the total diagnostic costs by 41.52 € per patient compared with PCR. The total cost difference was projected to be 31,892 € across a 14-week influenza season. The improved process and earlier diagnosis with the RDT pathway compared with conventional PCR resulted in considerable savings in ED, inpatient room occupancy time and cost across the influenza season.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30610515</PMID><DateCompleted><Year>2020</Year><Month>07</Month><Day>09</Day></DateCompleted><DateRevised><Year>2020</Year><Month>07</Month><Day>09</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1573-2614</ISSN><JournalIssue CitedMedium="Internet"><Volume>33</Volume><Issue>6</Issue><PubDate><Year>2019</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Journal of clinical monitoring and computing</Title><ISOAbbreviation>J Clin Monit Comput</ISOAbbreviation></Journal><ArticleTitle>Economic and operational impact of an improved pathway using rapid molecular diagnostic testing for patients with influenza-like illness in a German emergency department.</ArticleTitle><Pagination><MedlinePgn>1129-1138</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s10877-018-00243-2</ELocationID><Abstract><AbstractText>To evaluate the economic and operational effects of implementing a shorted diagnostic pathway during influenza epidemics. This retrospective study used emergency department (ED) data from the 2014/2015 influenza season. Alere i influenza A & B rapid molecular diagnostic test (RDT) was compared with the polymerase chain reaction (PCR) pathway. Differences in room occupancy time in the ED and inpatient ward and cost differences were calculated for the 14-week influenza season. The process flow was more streamlined with the RDT pathway, and the necessary isolation time in the ED was 9 h lower than for PCR. The difference in the ED examination room occupancy time was 2.9 h per patient on a weekday and 4 h per patient on a weekend day, and the difference in the inpatient room occupancy time was 2 h per patient on a weekday and 3 h per patient on a weekend day. Extrapolated time differences across the influenza season were projected to be 2733 h in the ED examination room occupancy and 1440 h in inpatient room occupancy. In patients with a negative diagnosis, the RDT was also estimated to reduce the total diagnostic costs by 41.52 € per patient compared with PCR. The total cost difference was projected to be 31,892 € across a 14-week influenza season. The improved process and earlier diagnosis with the RDT pathway compared with conventional PCR resulted in considerable savings in ED, inpatient room occupancy time and cost across the influenza season.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Brachmann</LastName><ForeName>Matthias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>bcmed GmbH, Neue Strasse 76, 89073, Ulm, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Witten/Herdecke University, 58448, Witten, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kikull</LastName><ForeName>Katja</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Ategris hospitals, CEO's Office, 45468, Muelheim, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kill</LastName><ForeName>Clemens</ForeName><Initials>C</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-7955-6700</Identifier><AffiliationInfo><Affiliation>Center for Emergency Medicine, Essen University Hospital, 45147, Essen, Germany. clemens.kill@uk-essen.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Betz</LastName><ForeName>Susanne</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Emergency Medicine, University Hospital Marburg, 35033, Marburg, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>01</Month><Day>04</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>J Clin Monit Comput</MedlineTA><NlmUniqueID>9806357</NlmUniqueID><ISSNLinking>1387-1307</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>J Clin Monit Comput. 2019 Feb 14;:</RefSource><PMID Version="1">30767135</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D004636" MajorTopicYN="N">Emergency Service, Hospital</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017048" MajorTopicYN="N">Health Care Costs</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007297" MajorTopicYN="N">Inpatients</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017146" MajorTopicYN="N">Models, Organizational</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D025202" MajorTopicYN="N">Molecular Diagnostic Techniques</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="Y">economics</QualifierName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016133" MajorTopicYN="N">Polymerase Chain Reaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Economic analysis</Keyword><Keyword MajorTopicYN="N">Emergency department</Keyword><Keyword MajorTopicYN="N">Influenza-like illness</Keyword><Keyword MajorTopicYN="N">Molecular test</Keyword><Keyword MajorTopicYN="N">Process optimization</Keyword><Keyword MajorTopicYN="N">Rapid diagnostic test</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>11</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>12</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>1</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>7</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>1</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">30610515</ArticleId><ArticleId IdType="doi">10.1007/s10877-018-00243-2</ArticleId><ArticleId 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IdType="pubmed">22257385</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country><region><li>Bade-Wurtemberg</li><li>District de Giessen</li><li>District de Tübingen</li><li>Hesse (Land)</li></region><settlement><li>Marbourg</li><li>Ulm</li></settlement></list><tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Brachmann, Matthias" sort="Brachmann, Matthias" uniqKey="Brachmann M" first="Matthias" last="Brachmann">Matthias Brachmann</name></region><name sortKey="Betz, Susanne" sort="Betz, Susanne" uniqKey="Betz S" first="Susanne" last="Betz">Susanne Betz</name><name sortKey="Brachmann, Matthias" sort="Brachmann, Matthias" uniqKey="Brachmann M" first="Matthias" last="Brachmann">Matthias Brachmann</name><name sortKey="Kikull, Katja" sort="Kikull, Katja" uniqKey="Kikull K" first="Katja" last="Kikull">Katja Kikull</name><name sortKey="Kill, Clemens" sort="Kill, Clemens" uniqKey="Kill C" first="Clemens" last="Kill">Clemens Kill</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|area= GrippeAllemagneV4
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:30610515
|texte= Economic and operational impact of an improved pathway using rapid molecular diagnostic testing for patients with influenza-like illness in a German emergency department.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:30610515" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a GrippeAllemagneV4
| This area was generated with Dilib version V0.6.35. |  |